Although the potential of Raman Optical Activity (ROA) spectroscopy in the field of organic and inorganic materials research has been well demonstrated, its practical application is still limited. This work shows historical background, current state of the art and challenges of ROA spectroscopy facing scientists today. Expectations and development prospects for the coming years are also discussed. Efforts have already been made to improve but also to properly interpret the ROA signal when the ROA technique is combined with other spectroscopies (i.e., ROA/Electronic Circular Dichroism and ROA/Circularly Polarized Luminescence). The paper shows how to intensify the ROA effect to shorten the spectrum accumulation time, control possible artefacts and support the analysis of ROA spectra with actual and new theoretical approaches. However, the challenge is to increase the interest in this technique among the academic community, develop reliable protocols and adapt them for practical use. National and international research networks can significantly contribute to the growth of methodologies and standardization in areas in which the ROA has so far been little used. This paper presents a perspective vision for the future progress of ROA alongside other chiroptical methods.

中文翻译：

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（共振）手性光学光谱中的拉曼光学活性：Quo vadis？

尽管拉曼光学活性（ROA）光谱在有机和无机材料研究领域的潜力已得到充分证明，但其实际应用仍然有限。这项工作展示了 ROA 光谱的历史背景、当前技术水平以及当今科学家面临的挑战。还讨论了未来几年的期望和发展前景。当ROA技术与其他光谱学（即ROA/电子圆二色性和ROA/圆偏振发光）结合时，已经做出了努力来改进并正确解释ROA信号。本文展示了如何增强 ROA 效应以缩短光谱积累时间、控制可能的伪影并用实际和新的理论方法支持 ROA 光谱分析。然而，面临的挑战是提高学术界对这项技术的兴趣，开发可靠的协议并使其适应实际应用。国家和国际研究网络可以为迄今为止很少使用 ROA 的领域的方法和标准化的发展做出重大贡献。本文对 ROA 与其他手性光学方法的未来进展提出了展望。