The identification of novel risk variants in the largest genome-wide association study of Raynaud phenomenon to date provides insights into the pathophysiology of the condition, including the potential role for α2A-adrenoceptors, and suggests opportunities for drug repurposing.

中文翻译：

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雷诺现象：从 GWAS 到药物再利用

迄今为止最大的雷诺现象全基因组关联研究中新风险变异的鉴定，提供了对该疾病病理生理学的深入了解，包括α2A-肾上腺素受体的潜在作用，并为药物重新利用提供了机会。