The presence of selected polybrominated diphenyl ethers (BDE-28, -47, -99, -100, -153, -154, and -183) was investigated in human milk samples collected from first-time mothers living in Zagreb, capital of Croatia. Samples from 2020 and 2010 were analyzed, and the first temporal comparison between the profiles and levels of these compounds in this area was obtained. A statistically significant difference between mass fractions depending on the sampling year was observed only for BDE-99, with values in 2020 higher than in 2010. BDE-153, whose median value (0.25 and 0.26 ng g⁻¹ lipid weight (l.w.) in 2010 and 2020, respectively) did not decrease in the 10-year period, was the most frequently detected congener in samples from both years. ΣPBDEs ranged from < LOD to 3.53 ng g⁻¹ l.w. (median 0.25 ng g⁻¹ l.w.), and from 0.14 to 6.75 ng g⁻¹ l.w. (median 0.55 ng g⁻¹ l.w.) in 2010 and 2020, respectively. Maternal age and reported fish consumption had no effect on observed PBDE mass fractions, while for BDE-153, positive significant correlation (p > 0.05) was observed of its detected mass fraction with mother’s body mass index (BMI) before pregnancy and after childbirth. Infants median estimated daily intake (EDI) via milk ingestion for ΣPBDE was higher in 2020 (3.221 ng kg⁻¹ bw day⁻¹) compared to 2010 (1.429 ng kg⁻¹ bw day⁻¹), but both values were well below threshold value, indicating that human milk consumption in this specific case is unlikely to raise health risks to infants.

对居住在克罗地亚首都萨格勒布的初为人母的母乳样本进行了调查，研究了选定的多溴二苯醚（BDE-28、-47、-99、-100、-153、-154 和 -183）的存在。对 2020 年和 2010 年的样品进行了分析，并获得了该地区这些化合物的概况和水平之间的首次时间比较。仅 BDE-99 的质量分数之间存在统计显着差异，具体取决于采样年份，2020 年的值高于 2010 年。BDE-153 的中值（0.25 和 0.26 ng g ^-1脂质重量 (lw)）分别是 2010 年和 2020 年）在这 10 年期间没有减少，是这两年样本中最常检测到的同源物。 2010 年和 2020 年，ΣPBDE 范围分别为 < LOD 至 3.53 ng g ⁻¹  lw（中位数 0.25 ng g ⁻¹  lw）和 0.14 至 6.75 ng g ⁻¹  lw（中位数 0.55 ng g ^{−1 lw）。}母亲年龄和报告的鱼类消费量对检测到的 PBDE 质量分数没有影响，而对于 BDE-153，其检测到的质量分数与母亲怀孕前和分娩后的体重指数 (BMI) 呈显着正相关 ( p  > 0.05)。^{与 2010 年（1.429 ng kg -1} bw day ^-1）相比，2020年婴儿通过牛奶摄入 ΣPBDE 的每日估计摄入量（EDI）中位数较高（3.221 ng kg ^-1  bw day ^-1），但这两个值均远低于阈值值，表明在这种特定情况下食用母乳不太可能增加婴儿的健康风险。