Mechanical properties of brain tissues are from principal features from different points of view; diagnosis, the performance of the brain and neurological disorders. Particularly viscoelastic properties of the brain tissues are determinative. In this study based on a proposed accurate and non-invasive method, we have measured the viscoelastic properties of prefrontal cortex and cerebellum, two important brain regions involved in motor learning and pathophysiology of autism spectrum disorder (ASD). In this regard, using photoacoustic systems, viscoelastic properties of tissues from the cerebellum and prefrontal cortex of normal and prenatal VPA (Valproic acid)-exposed (i.e. autistic-like) offspring rats are measured. Results of our study show that the cerebellums of normal tissues are stiffer than the tissue obtained from autistic-like rats, while the viscoelasticity of the prefrontal cortex of normal tissues is higher than that of autistic ones. The proposed method for the measurement of viscoelastic properties of the brain tissue has the potential not only for the fundamental studies but as a diagnosis technique.

脑组织的力学特性是从不同角度的主要特征；诊断、大脑和神经系统疾病的表现。特别是脑组织的粘弹性特性是决定性的。在这项基于准确和非侵入性方法的研究中，我们测量了前额皮质和小脑的粘弹性特性，这两个重要的大脑区域涉及运动学习和自闭症谱系障碍（ASD）的病理生理学。在这方面，使用光声系统，测量了正常和产前暴露于VPA（丙戊酸）（即自闭症样）后代大鼠的小脑和前额皮质组织的粘弹性特性。我们的研究结果表明，正常组织的小脑比自闭症样大鼠获得的组织更僵硬，而正常组织的前额叶皮层的粘弹性高于自闭症小鼠的组织。所提出的测量脑组织粘弹性特性的方法不仅具有基础研究的潜力，而且具有作为诊断技术的潜力。