Restless Legs Syndrome (RLS) is a neurological disorder primarily treated with pregabalin and gabapentin, followed by dopamine agonists later in the process due to the risk of augmenting RLS symptoms. In addition, clinical reports have disclosed varying degrees of success employing other agents in patients unresponsive to traditional agents. Here, we present a patient who had success in the reduction of RLS symptoms with lamotrigine, a broad-spectrum anticonvulsant. Previously, lamotrigine had been used in 2 trials with successful treatment of RLS.

中文翻译：

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用于治疗不宁腿综合征的抗惊厥药物：拉莫三嗪病例报告和文献综述。

不宁腿综合症 (RLS) 是一种神经系统疾病，主要使用普瑞巴林和加巴喷丁治疗，随后使用多巴胺激动剂治疗，因为存在加剧不宁腿综合症症状的风险。此外，临床报告还披露了在对传统药物无反应的患者中使用其他药物取得了不同程度的成功。在这里，我们介绍了一位患者，他使用拉莫三嗪（一种广谱抗惊厥药）成功减轻了 RLS 症状。此前，拉莫三嗪已在两项试验中成功治疗不宁腿综合征。