Flap fixation is the most promising solution to prevent seroma formation after mastectomy. In this systematic review with network meta-analysis (NMA), three different techniques were compared. The NMA included 25 articles, comprising 3423 patients, and revealed that sutures are superior to tissue glue in preventing clinically significant seroma. In addition, running sutures seemed to be superior to interrupted sutures. An RCT comparing these suture techniques seems necessary, given the quality and nature of existing literature.

中文翻译：

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乳房切除术后血清形成：不同皮瓣固定技术的系统回顾和网络荟萃分析

皮瓣固定是防止乳房切除术后血清肿形成最有希望的解决方案。在本次网络荟萃分析 (NMA) 系统综述中，比较了三种不同的技术。NMA 收录了 25 篇文章，涉及 3423 名患者，并揭示缝合线在预防临床上显着的血清肿方面优于组织胶。此外，连续缝合似乎优于间断缝合。考虑到现有文献的质量和性质，比较这些缝合技术的随机对照试验似乎是必要的。