Asthma associated with obesity is a chronic disease characterized by earlier airway remodeling, severe wheezing, and increased insensitivity to hormone therapy. Reticuline, a bioactive compound of Magnoliae Flos, exerts anti-inflammatory activity and can inhibit neutrophil recruitment. Thus, this study investigated the role of reticuline in obesity-related asthma.

中文翻译：

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网状蛋白对肥胖相关哮喘小鼠模型中 JAK2/STAT3/SOCS3 和 p38 MAPK/NF-κB 信号通路的抗炎作用

与肥胖相关的哮喘是一种慢性疾病，其特征是早期气道重塑、严重喘息以及对激素治疗不敏感。Reticuline 是木兰花的一种生物活性化合物，具有抗炎活性，并能抑制中性粒细胞募集。因此，本研究调查了网脉碱在肥胖相关哮喘中的作用。