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Green syhthesis of aluminium oxide nanoparticles using Chrysophyllum albidum, Terminalia catappa and Mimusops Coriacea leaf extracts for antibacterial and antifungal activities
Nano-Structures & Nano-Objects Pub Date : 2024-01-24 , DOI: 10.1016/j.nanoso.2024.101094
Olatunde S. Oladeji , Thokozani Xaba

The study reports an environmentally friendly and simple green technique for the synthesis of aluminium oxide nanoparticles (AlO NPs). The leaf extracts of (chry.A), (Alm) and (Lam) were used as reducing and stabilizing agents. Microscopic characterisations of the nanoparticles were carried out such as TEM, SEM, X-RAY, FTIR, UV and antimicrobial application were conducted. The result of the analysis showed that transmission electron microscopy (TEM) of AlO NPs revealed quasi-spherical particle shapes and showed the particle size distribution. X-ray diffraction (XRD) analysis revealed that the AlO crystals are face-centered cubic (FCC) for Chry.A AlO NP, Alm AlO NP and Lam AlO NP and the average crystallite size were given to be 54.4 nm, 58.3 nm and 25.8 nm while Fourier transform infrared (FTIR) results of AlO NPs showed the existence of metal-oxygen Al-O and occurrence of carbonyl and hydroxyl groups from plant flavonoids. The electronic interaction of AlO NPs was investigated with Ultraviolet visible spectroscopy (UV) and the results revealed 238 nm of the absorption capacity of AlO NPs which is attributed to quasi-spherical structural arrangement and energy dispersive X-ray spectroscopy (EDS) verified the existence of elemental aluminium which revealed maximum peaks of Al-O. The synthesized metal oxide nanoparticles (AlO NPs) were evaluated for antibacterial and antifungal actvitties and the results show that they were potent against gram-positive and The chry. A AlO NP was found to displayed higher activities of antibacterial against (gram-positive) than Alm AlO NP and Lam AlO NP. The antibacterial activities of Chry.A AlO NP and Alm AlO NP also showed maximum zone of inhibition with minimum inhibitory concentration MIC of 0.125 and 0.250 mg/mL respectively, which higher than ciprofloxacin with 0.625 mg/mL MIC. Antifungal potential investigated revealed MIC of 3.15, 6.25 and 12.5 mg/mL for Chry.A AlO NP, Alm AlO NP and Lam AlO NPs against and Therefore the use of novel extracts for the synthesis of AlO NPs has demonstrated good antimicrobial activities when compared to the control standard.

中文翻译:

使用 Chrysophyllum albidum、Terminalia catappa 和 Mimusops Coriacea 叶提取物绿色合成氧化铝纳米颗粒,具有抗菌和抗真菌活性

该研究报告了一种环保且简单的绿色合成氧化铝纳米颗粒(Al2O NP)的技术。(chry.A)、(Alm) 和 (Lam) 的叶提取物用作还原剂和稳定剂。对纳米粒子进行了微观表征,例如 TEM、SEM、X 射线、FTIR、UV 和抗菌应用。分析结果表明,Al2O 3 纳米颗粒的透射电子显微镜(TEM)显示出准球形颗粒形状并显示了颗粒尺寸分布。X 射线衍射 (XRD) 分析表明 Chry.A Al2O NP、Alm Al2O NP 和 Lam Al2O NP 的 Al2O 晶体为面心立方 (FCC),平均晶粒尺寸为 54.4 nm、58.3 nm 和25.8 nm,而Al2O NPs的傅里叶变换红外(FTIR)结果显示金属氧Al-O的存在以及植物黄酮类化合物中羰基和羟基的存在。利用紫外可见光谱 (UV) 研究了 Al2O 纳米粒子的电子相互作用,结果显示 Al2O 纳米粒子的 238 nm 吸收能力归因于准球形结构排列,能量色散 X 射线光谱 (EDS) 证实了其存在铝元素的分析显示了 Al-O 的最大峰。对合成的金属氧化物纳米粒子(Al2O NPs)进行了抗菌和抗真菌活性评估,结果表明它们对革兰氏阳性菌和细菌具有有效的作用。发现 A Al2O NP 比 Alm Al2O NP 和 Lam Al2O NP 表现出更高的抗菌活性(革兰氏阳性菌)。Chry.A AlO NP和Alm AlO NP的抗菌活性也显示出最大抑制区,最小抑菌浓度MIC分别为0.125和0.250 mg/mL,高于环丙沙星的0.625 mg/mL MIC。调查的抗真菌潜力显示,Chry.A Al2O NP、Alm Al2O NP 和 Lam Al2O NP 的 MIC 分别为 3.15、6.25 和 12.5 mg/mL,因此,与相比,使用新型提取物合成 Al2O NP 已表现出良好的抗菌活性。控制标准。
更新日期:2024-01-24
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