Background As the World Health Organization recommends, regular physical activity (PA) determines quality of life. The qualitative/quantitative characteristics of ideal PA to be suggested for inflammatory bowel diseases (IBD) nor the relationship with disease activity are not yet well defined. This study aimed to weigh PA levels and barriers/facilitators to PA in a cross-sectional group of patients with IBD. Methods Consecutive Italian non-severe IBD patients (assessed with partial Mayo score for and Harvey-Bradshaw index) received an anonymous online questionnaire to assess PA levels using the International Physical Activity Questionnaire (IPAQ), disease activity as Patient-Reported Outcomes 2 (PRO-2), and finally habits, beliefs, and barriers in conducting regular PA. Clinical, anthropometric, and demographic data were also collected. PA was processed as continuous units of resting metabolic rate in minutes/week (Met min/wk). Three PA groups were identified: inactive (< 700 Met min/wk), sufficiently active (700-2500 Met min/wk) and Health Enhancing PA (i.e., HEPA active, > 2500 Met min/wk) patients. Results The 219 patients enrolled exhibited overall PA levels of 834.5 Met min/wk, with a large proportion (94, 42.9%) classified as inactive. Only a minority (9, 4.1%) resulted as health-enhancing PA. Patients with a non-dyslipidaemia metabolic profile (p < 0.0001) or on biologics therapy (p=0.022) showed better IPAQ scores in moderate activities. PRO-2 correlated negatively with IPAQ intense activities scores (τ= -0.156, p=0.038) in ulcerative colitis patients. PRO-2 did not show notable sensitivity/specificity in predicting IPAQ inactivity (AUC < 0.6). IPAQ showed no notable differences when related to disease activity categories according to PRO-2 (p > 0.05). Physically active patients were more willing to discuss their PA with their IBDologists. Several barriers (e.g., diagnosis of IBD and fear of flare-ups after PA) are firmly rooted in physically inactive patients. Evacuation urgency (rectal syndrome) is the IBD-related barrier most physically inactive patients reported. Some fears about PA were worse felt in the absence of a stable partner (i.e., fear of worsening or recurrence of IBD, p < 0.05). Conclusion Many Italian IBD patients show a worrying rate of physical inactivity, depriving themselves of the multidimensional benefits that regular PA can bring. There is a need for IBDologists to act by removing barriers to PA and engaging in a regular discussion on the importance of PA with IBD patients. IPAQ has shown good feasibility and patient acceptance in this setting.

中文翻译：

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P1101 无论疾病活动性和 IBD 表型如何，在用国际体力活动问卷进行权衡时，患者报告的 IBD 患者的体力活动都值得关注：扩展的“BE-FIT-IBD”横断面研究中出现的障碍和促进因素

背景 正如世界卫生组织建议的那样，定期的体力活动 (PA) 决定生活质量。对于炎症性肠病 (IBD) 所建议的理想 PA 的定性/定量特征以及与疾病活动性的关系尚未明确定义。本研究旨在权衡 IBD 患者横断面组中的 PA 水平以及 PA 的障碍/促进因素。方法连续意大利非严重 IBD 患者（采用部分 Mayo 评分和 Harvey-Bradshaw 指数进行评估）接受匿名在线调查问卷，以使用国际身体活动问卷 (IPAQ) 评估 PA 水平，疾病活动作为患者报告结果 2 (PRO -2)，最后是进行定期 PA 的习惯、信念和障碍。还收集了临床、人体测量和人口统计数据。PA 被处理为以分钟/周为单位的静息代谢率连续单位 (Met min/wk)。确定了三个PA组：不活跃(＜700 Met min/wk)、足够活跃(700-2500 Met min/wk)和健康增强PA(即，HEPA活跃，＞2500 Met min/wk)患者。结果 纳入的 219 名患者的总体 PA 水平为 834.5 Met 分钟/周，其中很大一部分 (94, 42.9%) 被归类为不活动。只有少数人（9 人，4.1%）的 PA 改善了健康。具有非血脂异常代谢特征（p < 0.0001）或接受生物制剂治疗（p=0.022）的患者在中等活动中表现出更好的 IPAQ 评分。溃疡性结肠炎患者的 PRO-2 与 IPAQ 剧烈活动评分呈负相关（τ= -0.156，p=0.038）。PRO-2在预测IPAQ失活方面没有表现出显着的敏感性/特异性(AUC＜0.6)。根据 PRO-2，当与疾病活动类别相关时，IPAQ 没有显示出显着差异（p > 0.05）。身体活跃的患者更愿意与 IBD 专家讨论他们的 PA。一些障碍（例如 IBD 的诊断和对 PA 后病情发作的恐惧）在缺乏身体活动的患者中根深蒂固。大多数缺乏身体活动的患者报告称，紧急疏散（直肠综合征）是与 IBD 相关的障碍。在没有稳定伴侣的情况下，对 PA 的一些恐惧会更严重（即担心 IBD 恶化或复发，p < 0.05）。结论 许多意大利 IBD 患者缺乏身体活动的比例令人担忧，这使他们无法享受常规 PA 带来的多维益处。IBD 专家需要采取行动，消除 PA 障碍，并定期与 IBD 患者讨论 PA 的重要性。IPAQ 在这种情况下表现出了良好的可行性和患者接受度。