There are no data to evaluate the difference in populations and impact of centers with liver transplant programs in performing laparoscopic liver resection (LLR). This was a multicenter study including patients undergoing LLR for benign and malignant tumors at 27 French centers from 1996 to 2018. The main outcomes were postoperative severe morbidity and mortality. A total of 3154 patients were included, and 14 centers were classified as transplant centers (N = 2167 patients, 68.7 %). The transplant centers performed more difficult LLRs and more resections for hepatocellular carcinoma (HCC) in patients who more frequently had cirrhosis. A higher rate of performing the Pringle maneuver, a lower rate of blood loss and a higher rate of open conversion (all p < 0.05) were observed in the transplant centers. There was no association between the presence of a liver transplant program and either postoperative severe morbidity (<10 % in each group; p = 0.228) or mortality (1 % in each group; p = 0.915). Most HCCs, difficult LLRs, and cirrhotic patients are treated in transplant centers. We show that all centers can achieve comparable safety and quality of care in LLR independent of the presence of a liver transplant program.

中文翻译：

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比较有和没有肝移植计划的中心之间腹腔镜肝切除术的适应症、复杂性和结果：一项法国全国性研究

没有数据可以评估人群差异以及开展肝移植项目的中心在进行腹腔镜肝切除术 (LLR) 方面的影响。这是一项多中心研究，包括 1996 年至 2018 年在法国 27 个中心接受良性和恶性肿瘤 LLR 治疗的患者。主要结果是术后严重发病率和死亡率。总共纳入了 3154 名患者，其中 14 个中心被归类为移植中心（N = 2167 名患者，68.7%）。移植中心对更常患有肝硬化的患者进行了更困难的 LLR 和更多的肝细胞癌 (HCC) 切除术。在移植中心观察到执行 Pringle 操作的比率较高，失血率较低，开放转换率较高（所有 p < 0.05）。肝移植计划的存在与术后严重发病率（每组<10%；p = 0.228）或死亡率（每组1%；p = 0.915）之间没有关联。大多数 HCC、困难 LLR 和肝硬化患者在移植中心接受治疗。我们表明，无论是否存在肝移植计划，所有中心都可以在 LLR 中实现相当的安全性和护理质量。