Endovascular thrombectomy for acute ischemic stroke in Saudi Arabia: A single-center experience,Journal of Stroke & Cerebrovascular Diseases

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Endovascular thrombectomy for acute ischemic stroke in Saudi Arabia: A single-center experience
Journal of Stroke & Cerebrovascular Diseases ( IF 2.5 ) Pub Date : 2024-01-25 , DOI: 10.1016/j.jstrokecerebrovasdis.2023.107552
Hanan Alhazmi , Omar K. Ameen , Ziyad Almalki , Abdulmajeed Alanazi , Ali Albalawi , Mahmoud Alshanqiti , Khalid Almalki , Ali Alsaleh , Alaa Khayat , Hatim Ibrahim , Ibrahim A. Almulhim , Abdulrahman Jubran , Nehal Almodarra , Nouf Almansour , Saud A. Alnaaim , Fahmi Al-Senani , Ashfaq Shuaib , Jamal Muthana , Mohammed Alotaibi

Purpose

This study aimed to investigate the outcomes of endovascular thrombectomy-treated patients in King Fahad Medical City, Riyadh, Saudi Arabia.

Methods

A retrospective cohort study of acute ischemic stroke patients treated with endovascular thrombectomy. Patients were included in the study between January 2015 and December 2022. Good outcomes were defined as a modified Rankin Scale (mRS) of 0–2 at 90 days. Multivariate logistic regression analysis was performed to identify the independent factors associated with good outcomes.

Results

During the study period, 369 patients with acute ischemic stroke (mean ± SD age, 61/- 15.1 yrs; 55.4 % male) underwent mechanical thrombectomy. Median National Institute of Health Stroke Scale (NIHSS) 15. Intravenous thrombolysis was administered to 34.5 % of the patients. Successful recanalization in the anterior circulation was achieved in 84.8 % of patients. Data from mRS performed after 90 days in the anterior circulation were available for 71.2 % of the patients. Of these, 41 % showed a good outcome, and the mortality rate was 22.4 %. The significant factors associated with good outcomes were age, NIHSS score, Alberta Stroke Program Early Computed Tomography Score (ASPECTS), and short arterial puncture to recanalization.

Conclusion

The number of patients who underwent endovascular thrombectomy has increased over time. The treatment outcomes and mortality were comparable with those of previous endovascular thrombectomy registries despite the high prevalence of DM, lower ASPECT score, and prolonged onset-to-recanalization time.

中文翻译：

沙特阿拉伯血管内血栓切除术治疗急性缺血性卒中：单中心经验

目的

本研究旨在调查沙特阿拉伯利雅得法赫德国王医疗城接受血管内血栓切除术治疗的患者的结果。

方法

接受血管内血栓切除术治疗的急性缺血性卒中患者的回顾性队列研究。患者于 2015 年 1 月至 2022 年 12 月期间纳入研究。良好结果的定义为 90 天时改良 Rankin 量表 (mRS) 为 0-2。进行多变量逻辑回归分析以确定与良好结果相关的独立因素。

结果

在研究期间，369 名急性缺血性中风患者（平均±SD 年龄，61/- 15.1 岁；55.4% 男性）接受了机械血栓切除术。美国国立卫生研究院卒中量表 (NIHSS) 中位数为 15。34.5% 的患者接受了静脉溶栓治疗。84.8% 的患者成功实现前循环再通。71.2% 的患者可获得前循环 90 天后进行的 mRS 数据。其中，41%的患者预后良好，死亡率为22.4%。与良好结果相关的重要因素是年龄、NIHSS 评分、艾伯塔省中风计划早期计算机断层扫描评分 (ASPECTS) 以及动脉穿刺至再通时间短。