Abstract

The work is devoted to the study of the capacity for chiral recognition during the adsorption process of hippuric acid crystals obtained by the temperature gradient method under Viedma ripening conditions. This method is distinguished by the fact that the primary violation of chiral equilibrium between the nuclei formed during crystallization is not caused by the mechanical action of the stirrer but by crystallization at low temperatures. Limonenes and α-pinenes were used as test enantiomers. Adsorption isotherms were obtained using inverse gas chromatography, and their analysis made it possible to establish the chiral recognition ability of the surface. It was shown that both the enantioselectivity and adsorption capability of the synthesized hippuric acid crystals were significantly higher than those of crystals obtained under classical Viedma ripening conditions. High surface heterogeneity is probably the reason for this phenomenon.

中文翻译：

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使用温度梯度在别德马成熟条件下获得的马尿酸晶体上对映体的吸附等温线

摘要

本工作致力于研究温度梯度法获得的马尿酸晶体在Viedma熟化条件下吸附过程中的手性识别能力。该方法的特点是，结晶过程中形成的核之间手性平衡的主要破坏不是由搅拌器的机械作用引起的，而是由低温下的结晶引起的。使用柠檬烯和α-蒎烯作为测试对映体。使用反气相色谱法获得吸附等温线，对其分析可以确定表面的手性识别能力。结果表明，合成的马尿酸晶体的对映选择性和吸附能力均显着高于经典Viedma熟化条件下获得的晶体。高表面异质性可能是造成这种现象的原因。