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Celecoxib Catalyzed the Coupling Reaction of Epoxide and CO2
Letters in Organic Chemistry ( IF 0.8 ) Pub Date : 2024-01-24 , DOI: 10.2174/0115701786276731231206113215
Ling Wu 1 , Xiaocheng Xia 1 , Wenying An 1 , Wenshan Cui 1 , Yue Liu 1 , Wei Lv 1 , Fengtian Wu 1
Affiliation  

In this study, high yields of various cyclic carbonates are obtained by employing the drug celecoxib to promote the coupling reaction of CO2 and epoxide using tetrabutylammonium bromide. This strategy enables the synthesis of benzoic acid, phenylpropiolic acid, and 2, 4- quinazolinedione. In addition, the model reaction mechanism is proposed.

中文翻译:

塞来昔布催化环氧化物与CO2的偶联反应

在本研究中,通过使用药物塞来考昔促进四丁基溴化铵与环氧化物的偶联反应,获得了高产率的各种环状碳酸酯。该策略能够合成苯甲酸、苯丙炔酸和2, 4-喹唑啉二酮。此外,还提出了模型反应机理。
更新日期:2024-01-24
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