CineECG offers a visual representation of the location and direction of the average ventricular electrical activity throughout a single cardiac cycle, based on the 12‑lead ECG. Currently, CineECG has not been used to visualize ventricular activation patterns during ischemia. To determine the changes in ventricular activity during acute ischemia with the use of CineECG, and relating this to changes in the ECG. Continuous ECG's during percutaneous coronary intervention with prolonged balloon inflation from the STAFF III database were analyzed with CineECG at baseline and every 10 s throughout the first 150 s of balloon inflation. The CineECG direction was determined for the initial QRS-complex, terminal QRS-complex, ST-segment and T-wave. Changes in the CineECG were quantified by calculating the between the direction at baseline and the direction at every 10 s of inflation. Additionally, the root mean square amplitude (rmsA) of the ST-segment was computed. 94 patients were included. At start inflation, the median was 14.7° [7.5–33.4], 21.8° [11.4–34.2], 20.6° [8.0–43.9], and 23.5° [11.8–48.0] for the initial QRS-complex, terminal QRS-complex, ST-segment and T-wave, respectively. Meanwhile, the median rmsA increased from 0.039 mV [0.027–0.058] at baseline to 0.045 mV [0.033–0.075] at start of inflation. CineECG was able to detect immediate changes in ventricular electrical activity during induced ischemia, while changes in the ST-segment of the ECG were still subtle. Therefore, CineECG might support the early detection of acute ischemia, even before distinct ECG changes become visible.

中文翻译：

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CineECG 用于可视化缺血期间心室电活动的变化

CineECG 基于 12 导联心电图，以视觉方式表示整个心动周期中平均心室电活动的位置和方向。目前，CineECG 尚未用于可视化缺血期间的心室激活模式。使用 CineECG 确定急性缺血期间心室活动的变化，并将其与心电图的变化联系起来。使用 CineECG 在基线和球囊充气的前 150 秒内每 10 秒对来自 STAFF III 数据库的经皮冠状动脉介入治疗期间长时间球囊充气期间的连续心电图进行分析。CineECG 方向是针对初始 QRS 复合波、终端 QRS 复合波、ST 段和 T 波确定的。通过计算基线方向和每 10 秒膨胀时的方向之间的关系来量化 CineECG 的变化。此外，还计算了 ST 段的均方根振幅 (rmsA)。包括 94 名患者。开始充气时，初始 QRS 波群、终末 QRS 波群的中位数为 14.7° [7.5–33.4]、21.8° [11.4–34.2]、20.6° [8.0–43.9] 和 23.5° [11.8–48.0] 、 ST 段和 T 波，分别。同时，中位 rmsA 从基线时的 0.039 mV [0.027–0.058] 增加到充气开始时的 0.045 mV [0.033–0.075]。CineECG 能够检测诱发缺血期间心室电活动的即时变化，而心电图 ST 段的变化仍然很细微。因此，CineECG 可能支持急性缺血的早期检测，甚至在明显的心电图变化变得可见之前。