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Establishing a fingerprinting method for fast catheter identification in HDR brachytherapy in vivo dosimetry
Brachytherapy ( IF 1.9 ) Pub Date : 2024-01-28 , DOI: 10.1016/j.brachy.2023.10.004
Daline Tho , Cédric Bélanger , Erik B. Jørgensen , Jérémie Tanguay , Haydee M.L. Rosales , Sam Beddar , Jacob G. Johansen , Gustavo Kertzscher , Marie-Claude Lavallée , Luc Beaulieu

To use quantities measurable during dosimetry to build unique channel identifiers, that enable detection of brachytherapy errors. Treatment plan of 360 patients with prostate cancer who underwent high-dose-rate brachytherapy (range, 16–25 catheters; mean, 17) were used. A single point virtual dosimeter was placed at multiple positions within the treatment geometry, and the source-dosimeter distance and dwell time were determined for each dwell position in each catheter. These values were compared across all catheters, dwell position by dwell position, simulating a treatment delivery. A catheter was considered uniquely identified if, for a given dwell position, no other catheters had the same measured values. The minimum number of dwell positions needed to identify a specific catheter and the optimal dosimeter location uniquely were determined. The radial (r) and vertical (z) dimensions of the source-dosimeter distance were also examined for their utility in discriminating catheters. Using a virtual dosimeter with no uncertainties, all catheters were identified in 359 of the 360 cases with 9 dwell position measurements. When only the dwell time were measured, all catheters were uniquely identified after 1 dwell position. With a 2-mm spatial accuracy (r,z), all catheters were identified in 94% of the plans. Simultaneous measurement of source-dosimeter distance and dwell time ensured full catheter identification in all plans ranging from 2 to 6 dwell positions. The number of dwell positions needed to uniquely identify all catheters was lower when the distance from the implant center was higher. The most efficient fingerprinting approach involved combining source-dosimeter distance (i.e., source tracking) and dwell time. The further the dosimeter is placed from the center of the implant the better it can uniquely identify catheters.

中文翻译:

建立 HDR 近距离放射治疗体内剂量测定中快速导管识别的指纹识别方法

使用剂量测定过程中可测量的量来构建唯一的通道标识符,从而能够检测近距离放射治疗错误。使用了 360 名接受高剂量近距离放射治疗的前列腺癌患者的治疗计划(范围,16-25 个导管;平均,17 个)。将单点虚拟剂量计放置在治疗几何结构内的多个位置,并确定每个导管中每个驻留位置的源-剂量计距离和驻留时间。对所有导管的这些值进行比较,逐个停留位置,模拟治疗递送。如果对于给定的停留位置,没有其他导管具有相同的测量值,则认为导管被唯一标识。确定了识别特定导管所需的最小驻留位置数量和唯一的最佳剂量计位置。还检查了源-剂量计距离的径向(r)和垂直(z)尺寸在区分导管中的效用。使用无不确定性的虚拟剂量计,通过 9 次驻留位置测量,在 360 例病例中的 359 例中识别出所有导管。当仅测量停留时间时,所有导管在 1 个停留位置后被唯一识别。空间精度 (r,z) 为 2 毫米,94% 的计划中的所有导管均被识别。同时测量源-剂量计距离和驻留时间可确保在 2 至 6 个驻留位置的所有计划中完全识别导管。当距种植体中心的距离较高时,唯一识别所有导管所需的驻留位置数量较少。最有效的指纹识别方法涉及将源-剂量计距离(即源跟踪)和停留时间结合起来。剂量计距离植入物中心越远,它就能更好地唯一识别导管。
更新日期:2024-01-28
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