Evidence on the long-term effects of reducing sedentary behaviour (SB) on blood pressure (BP) is scarce. Therefore, we performed a sub-analysis of the BP effects of a six-month intervention that aimed at reducing SB by 1 h/day and replacing it with non-exercise activities. Sixty-four physically inactive and sedentary adults with metabolic syndrome (58% female, 58 [SD 7] years, BP 143/88 [16/9] mmHg, SB 10 [1] h/day) were randomised into intervention (INT, n = 33) and control (CON, n = 31) groups. Resting BP and BP at each stage during and after a graded maximal bicycle ergometer test were measured before and after the intervention. SB, standing, moderate-to-vigorous physical activity (MVPA), and light physical activity (LPA) were measured in six-second intervals at baseline and during the whole six-month intervention using hip-worn accelerometers. The analyses were adjusted for BP medication status. The intervention resulted in a 40 min/day reduction in SB and concomitant 20 min/day increase in MVPA. Resting systolic BP was lower in the CON group before and after the intervention. No group x time interactions were observed in resting BP or BP during exercise at submaximal or maximal intensities, or during recovery. The changes in LPA and MVPA were inversely correlated with the changes in BP during light-to-moderate intensity exercise. An intervention that resulted in a 40 min/day reduction in SB for six months was not sufficient at influencing BP at rest, during or after exercise in adults with metabolic syndrome. However, successfully increasing LPA or MVPA might lower BP during light-to-moderate-intensity activities.

关于减少久坐行为 (SB) 对血压 (BP) 的长期影响的证据很少。因此，我们对为期 6 个月的干预措施的血压效应进行了子分析，该干预措施旨在将 SB 减少 1 小时/天，并用非运动活动代替。64 名身体缺乏活动且久坐的代谢综合征成年人（58% 为女性，58 [SD 7] 岁，血压 143/88 [16/9] mmHg，SB 10 [1] 小时/天）被随机分配至干预组（INT、n  = 33) 和对照 (CON, n  = 31) 组。在干预前后测量静息血压和分级最大自行车测功机测试期间和之后每个阶段的血压。在基线和整个六个月的干预期间，使用髋部佩戴的加速度计以六秒的间隔测量 SB、站立、中度至剧烈体力活动 (MVPA) 和轻度体力活动 (LPA)。根据血压药物状态调整分析。干预导致 SB 减少 40 分钟/天，同时 MVPA 增加 20 分钟/天。CON 组在干预前后的静息收缩压较低。在静息血压或次最大或最大强度运动期间或恢复期间的血压中，没有观察到组x时间交互作用。LPA和MVPA的变化与轻度至中强度运动期间血压的变化呈负相关。对于患有代谢综合征的成年人来说，导致 SB 每天减少 40 分钟、持续六个月的干预措施不足以影响静息时、运动期间或运动后的血压。然而，成功增加 LPA 或 MVPA 可能会降低轻度至中等强度活动期间的血压。