Strachan’s syndrome comprises a triad of optic, auditory and painful sensory peripheral neuropathy. It has been recognised since the late 19th century and is presumed to result from nutritional deficiency. Patients present acute or subacutely after a period of systemic illness, weight loss or, most commonly, dietary restriction, especially veganism, which can cause riboflavin (vitamin B2) and vitamin B12 deficiencies. The syndrome is more common in people who are black British and often of Jamaican descent. We describe the clinical phenotype using a typical case example, review other endemic nutritional peripheral neuropathies and discuss the potential benefit of riboflavin as a treatment. Data sharing not applicable as no datasets generated and/or analysed for this study.

中文翻译：

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Strachan 综合征和核黄素缺乏

斯特拉坎综合征包括视、听和疼痛性感觉周围神经病变三联征。自 19 世纪末以来，人们就已认识到这种情况，并推测是由营养缺乏引起的。患者在一段时间的全身性疾病、体重减轻或最常见的饮食限制（尤其是素食主义）后出现急性或亚急性症状，这可能导致核黄素（维生素 B2）和维生素 B12 缺乏。这种综合症在英国黑人（通常是牙买加裔）中更为常见。我们使用典型病例描述临床表型，回顾其他地方性营养性周围神经病，并讨论核黄素作为治疗的潜在益处。数据共享不适用，因为本研究没有生成和/或分析数据集。