Purpose

This study aimed to investigate the influence factors of financial toxicity experienced by colorectal cancer patients after surgery. The results will provide deep insights for developing effective intervention strategies to address this common issue of colorectal cancer care.

Methods

In this cross-sectional study, we recruited 213 postoperative patients with colorectal cancer from February 2023 to July 2023 in two major public hospitals. Patients completed the General Information Questionnaire, Comprehensive Scores for Financial Toxicity (COST), Self-perceived Burden Scale (SPBS), Family Resilience Questionnaire (FaREQ), and Social Support Rating Scale (SSRS). A multiple linear regression model was used to investigate the influence factors of financial toxicity.

Results

The mean score of financial toxicity was medium (18.91 ± 7.90) in this study. Financial toxicity score was negatively correlated with self-perceived burden (r = −0.333, P < 0.01) and positively associated with family resilience (r = 0.365, P < 0.01) and social support (r = 0.388, P < 0.01). Via multiple linear regression analysis, we identified seven significant factors associated with financial toxicity, including family income [(95 %CI: 1.075–3.123); P = 0.000], self-perceived burden [(95 %CI: 0.300∼-0.038); P = 0.012], stoma [(95 %CI: 5.309∼-1.682); P = 0.000], social support [(95 %CI:0.058–0.407); P = 0.009], cancer stage [(95 %CI: 2.178∼-0.170); P = 0.022], postoperative duration [(95 %CI: 1.900∼-0.332); P = 0.005], and family resilience [(95 %CI: 0.028–0.203); P = 0.010].

Conclusions

Financial toxicity was prevalent among postoperative colorectal cancer patients. Additional support and early interventions should be given to high-risk patients, including those with stomas, advanced disease stages, or experiencing longer postoperative duration. Apart from demographic factors, we identified that self-perceived burden, family resilience, and social support were also associated with financial toxicity, providing a new perspective for developing effective strategies against financial toxicity.

中文翻译：

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结直肠癌护理中术后经济毒性及其影响因素：横断面研究

目的

本研究旨在探讨结直肠癌患者术后经济毒性的影响因素。研究结果将为制定有效的干预策略来解决结直肠癌护理的这一常见问题提供深刻的见解。

方法

在这项横断面研究中，我们招募了2023年2月至2023年7月期间两家大型公立医院的213名结直肠癌术后患者。患者完成一般信息问卷、财务毒性综合评分（COST）、自我感知负担量表（SPBS）、家庭复原力问卷（FaREQ）和社会支持评定量表（SSRS）。采用多元线性回归模型研究金融毒性的影响因素。

结果

本研究中财务毒性的平均得分为中等（18.91±7.90）。财务毒性评分与自我感知负担呈负相关（r  = -0.333，P < 0.01），与家庭复原力（ r  = 0.365，P  < 0.01）和社会支持 呈正相关（ r  = 0.388，P  < 0.01）。通过多元线性回归分析，我们确定了与财务毒性相关的七个重要因素，包括家庭收入[(95%CI: 1.075–3.123)；P  = 0.000]，自我感知负担[(95%CI: 0.300∼-0.038)；P  = 0.012]，造口[(95%CI：5.309∼-1.682)；P  = 0.000]，社会支持[(95%CI：0.058–0.407)；P  = 0.009]，癌症分期[(95%CI：2.178∼-0.170)；P  = 0.022]，术后持续时间[(95%CI：1.900∼-0.332)；P  = 0.005] 和家庭复原力 [(95%CI: 0.028–0.203); P  = 0.010]。

结论

经济毒性在结直肠癌术后患者中普遍存在。应向高危患者提供额外的支持和早期干预，包括有造口、疾病晚期或术后持续时间较长的患者。除了人口因素外，我们还发现自我感知的负担、家庭弹性和社会支持也与财务毒性有关，这为制定有效的应对财务毒性策略提供了新的视角。