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H2O2 Self-supplying CaO2/CuO2/Fe3O4 Nanoplatform for Enhanced Chemodynamic Therapy of Cancer Cells
ChemNanoMat ( IF 3.8 ) Pub Date : 2024-02-01 , DOI: 10.1002/cnma.202300540
Bojian Liu 1 , Xiaohui Wang 2 , Wei Yang 1 , Hongshang Peng 3 , Hongxin Zhang 1
Affiliation  

We have synthesized a hyaluronic acid (HA) modified CaO2/CuO2/Fe3O4 nanocomposite by a simple and flexible strategy. The H2O2 self-supplying and ⋅OH self-catalyzed nanocomposite exhibited favorable pH-controlled ⋅OH generation and excellent tumor growth inhibition ability, providing a potential nanotheranostics platform with active targeting and favorable therapeutic efficacy in tumor therapy.

中文翻译:

H2O2 自供给 CaO2/CuO2/Fe3O4 纳米平台用于增强癌细胞的化学动力学治疗

我们通过简单灵活的策略合成了透明质酸(HA)修饰的CaO 2 /CuO 2 /Fe 3 O 4纳米复合材料。H 2 O 2自供给和·OH自催化纳米复合材料表现出良好的pH控制·OH生成和优异的肿瘤生长抑制能力,为肿瘤治疗提供了一个具有主动靶向性和良好治疗效果的潜在纳米治疗平台。
更新日期:2024-02-01
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