Post stroke sleep duration could increase the risk of death. This study tested the hypothesis that inadequate sleep duration is associated with increased mortality among stroke survivors. The REasons for Geographic And Racial Differences in Stroke (REGARDS), a national population-based longitudinal study, was the data source. Sleep duration was ascertained between 2013 and 2016 among stroke survivors who were subsequently followed up until death or censored on December 31, 2022. Sleep duration was estimated as the difference between wake-up time and bedtime to which was subtracted the time spent in bed without sleep. Cox proportional hazards regression models were employed to investigate the association between sleep duration and all-cause mortality adjusting for demographic factors, socioeconomic factors, behavioral factors, and co-morbidities. A total of 468 non-Hispanic Black and White stroke survivors were included in this analysis. The mean age was 76.3 years, 52.6% were females and 56.0% were non-Hispanic White individuals. The distribution of short (≤6 h), adequate (7.0–8.9 h), and long sleep (≥9 h) was 30.3%, 44.7%, and 25%, respectively. Over a mean follow-up of 5.0 years, 190 (40.6%) deaths occurred. Compared to stroke survivors with adequate sleep (7.0–8.9 h), stroke survivors with long sleep (≥9 h) were at increased risk of all-cause mortality (HR=1.46, 95% CI=1.01, 2.12). However, short sleep (≤6 h) was not significantly associated with an increased risk of all-cause mortality (HR=1.31, 95% CI=0.90, 1.91). Subgroup analyses indicated higher risk in the age <75 years, females, non-Hispanic Black individuals, and those living in the Stroke Belt region, but those differences were not statistically significant. In this study of stroke survivors, 9 hours or more of sleep per day was associated with an increased risk of all-cause mortality. This finding suggests that excessive sleep duration may be a warning sign of poor life expectancy in stroke survivors.

中文翻译：

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中风幸存者的睡眠时间和全因死亡率

中风后睡眠时间可能会增加死亡风险。这项研究检验了睡眠时间不足与中风幸存者死亡率增加相关的假设。数据来源是“卒中地理和种族差异的原因”(REGARDS)，这是一项基于全国人口的纵向研究。2013 年至 2016 年间，中风幸存者的睡眠持续时间被确定，这些幸存者随后被随访直至死亡或于 2022 年 12 月 31 日进行审查。睡眠持续时间的估计为起床时间和就寝时间之间的差值，减去在床上度过的时间，而无需考虑睡眠时间。睡觉。采用 Cox 比例风险回归模型来研究睡眠时间与全因死亡率之间的关联，并根据人口因素、社会经济因素、行为因素和合并症进行调整。本次分析共纳入 468 名非西班牙裔黑人和白人中风幸存者。平均年龄为 76.3 岁，其中 52.6% 为女性，56.0% 为非西班牙裔白人。短睡眠（≤6小时）、充足睡眠（7.0-8.9小时）和长睡眠（≥9小时）的分布分别为30.3%、44.7%和25%。在平均 5.0 年的随访中，发生了 190 例（40.6%）死亡。与睡眠充足（7.0-8.9小时）的中风幸存者相比，睡眠时间长（≥9小时）的中风幸存者全因死亡风险增加（HR=1.46，95% CI=1.01，2.12）。然而，睡眠时间短（≤6 小时）与全因死亡风险增加并无显着相关性（HR=1.31，95% CI=0.90，1.91）。亚组分析表明，年龄 <75 岁、女性、非西班牙裔黑人和居住在中风带地区的人的风险较高，但这些差异不具有统计学意义。在这项针对中风幸存者的研究中，每天睡眠 9 小时或以上与全因死亡风险增加相关。这一发现表明，睡眠时间过长可能是中风幸存者预期寿命不佳的警告信号。