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Nine years of imported malaria in a teaching hospital in Belgium: Demographics, clinical characteristics, and outcomes
Diagnostic Microbiology and Infectious Disease ( IF 2.9 ) Pub Date : 2024-02-02 , DOI: 10.1016/j.diagmicrobio.2024.116206
Ratovonjanahary T , Danwang C , Robert A , Yombi JC

Imported malaria is often misdiagnosed due to the aspecific symptoms and lack of familiarity among clinicians. This study aims to evaluate a decade-long trend of imported malaria cases in a Belgian teaching hospital by analyzing demographics, clinical characteristics, and outcomes. Medical records of 223 patients with confirmed malaria diagnoses between 2010 and 2019 were analyzed. Most patients were male (63.2%), aged 18-65 years (77.1%), and visiting friends or relatives (40.8%). Central Africa was the most common travel destination (54.3%), and 63.7% did not take prophylaxis. Symptoms were flu-like, with fever (91.9%) being most prevalent. P. was identified in 88.3% of cases. A high proportion of severe cases (41.7%) and a low mortality rate (0.9%) were recorded. A severe form of the disease is associated with a more extended hospital stay than uncomplicated form (median of 5 vs. 4 days, p < 0.001). Thirty-five-point five percent [33/93] of patients with severe malaria have had a previous malaria infection compared to 50.8% [66/130] of uncomplicated patients (p= 0.013) wich was statistically significant. Malaria disproportionately affects VFRs traveling to Central Africa, and flu-like symptoms should raise suspicion. Prophylaxis is essential to prevent the disease, and early diagnosis is critical for effective management. A severe form of the disease is associated with a more extended hospital stay than uncomplicated form and people with a previous history of malaria have a less severe disease

中文翻译:

比利时一所教学医院九年的输入性疟疾:人口统计、临床特征和结果

由于输入性疟疾症状不特异性以及临床医生对疟疾缺乏了解,经常被误诊。本研究旨在通过分析人口统计、临床特征和结果来评估比利时一家教学医院十年来输入性疟疾病例的趋势。分析了 2010 年至 2019 年间 223 名确诊疟疾患者的医疗记录。大多数患者为男性(63.2%),年龄在18-65岁(77.1%),以及探亲访友(40.8%)。中部非洲是最常见的旅行目的地(54.3%),63.7% 的人没有采取预防措施。症状与流感类似,其中最常见的是发烧(91.9%)。88.3% 的病例中发现了 P.。重症病例比例较高(41.7%),死亡率较低(0.9%)。与无并发症的疾病相比,严重疾病的住院时间更长(中位数为 5 天与 4 天,p < 0.001)。35% [33/93] 的重症疟疾患者曾感染过疟疾,而无并发症患者的这一比例为 50.8% [66/130] (p= 0.013),具有统计学意义。疟疾对前往中非的 VFR 的影响尤为严重,流感样症状应引起怀疑。预防对于预防该疾病至关重要,早期诊断对于有效治疗至关重要。与无并发症的疟疾相比,严重的疟疾会导致住院时间更长,而有疟疾病史的人病情较轻
更新日期:2024-02-02
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