This study aimed to investigate the genetic diversity of 108 geographically and temporally diverse strains of using a multi-locus sequence typing scheme (MLST). We extracted MLST data of 87 strains from PubMLST database and retrieved MLST gene sequences from 21 complete genomes of available in GenBank database. MLST scheme identified 65 Sequence types (STs), which were grouped into five clonal complexes (CC) and 47 singletons. Phylogenetic analysis revealed that the majority of isolates were clustered according to their country of origin, showing some significant specificity trends for the nation. Although recombination was detected, it was not significant enough to alter the clonal population structure of . In sum, MLST scheme provides insightful data on the phylogenetics of international strains of , arguing for the existence of genetically differentiable STs according to their origin of isolation.

中文翻译：

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人型支原体地理和时间上不同菌株的多位点序列分型

本研究旨在使用多位点序列分型方案 (MLST) 调查 108 个地理和时间上不同的菌株的遗传多样性。我们从PubMLST数据库中提取了87个菌株的MLST数据，并从GenBank数据库中可用的21个完整基因组中检索了MLST基因序列。MLST 方案识别了 65 种序列类型 (ST)，分为 5 种克隆复合体 (CC) 和 47 种单体。系统发育分析显示，大多数分离株根据其原产国进行聚类，显示出该国家的一些显着的特异性趋势。尽管检测到重组，但其影响还不足以改变 的克隆群体结构。总之，MLST 方案提供了关于国际毒株系统发育的深刻数据，根据其分离起源论证了遗传上可区分的 ST 的存在。