Cell stresses occur in a wide variety of settings: in disease, during industrial processes, and as part of normal day-to-day rhythms. Adaptation to these stresses requires cells to alter their proteome. Cells modify the proteins they synthesize to aid proteome adaptation. Changes in both mRNA transcription and translation contribute to altered protein synthesis. Here, we discuss the changes in translational mechanisms that occur following the onset of stress, and the impact these have on stress adaptation.

中文翻译：

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应对压力的翻译监管

细胞应激发生在多种环境中：在疾病中、在工业过程中以及作为正常日常节律的一部分。适应这些压力需要细胞改变其蛋白质组。细胞修改它们合成的蛋白质以帮助蛋白质组适应。 mRNA 转录和翻译的变化都会导致蛋白质合成的改变。在这里，我们讨论压力发生后发生的转化机制的变化，以及这些变化对压力适应的影响。