The use of Left Atrial Appendage (LAA) occluder devices has been on the rise in patients with atrial fibrillation. Studies regarding the long-term risks of occluder devices remain sparse. In this brief report, we discuss the unusual case of an 85-year-old female with long-term complication from Left Atrial Appendage (LAA) closure: Device-Related Thrombus (DRT) about two years after insertion. Compared to the expected stroke rate without anticoagulation, patients with DRT on their LAAO device still had a 28% relative reduction in ischemic stroke. This suggests that these strokes may have emanated from alternate etiologies other than the DRT. Patients with active or known history of cancer appears to have a higher risk of DRT. More data is needed on this topic to augment awareness and understanding of LAAO complications and DRT management strategies.

中文翻译：

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左心耳封堵术后数年与隐匿性恶性肿瘤相关的晚期装置相关血栓

心房颤动患者中左心耳 (LAA) 封堵器的使用呈上升趋势。关于封堵器长期风险的研究仍然很少。在这份简短的报告中，我们讨论了一名 85 岁女性的罕见病例，她因左心耳 (LAA) 封堵术而出现长期并发症：植入后约两年出现器械相关血栓 (DRT)。与未进行抗凝治疗的预期中风发生率相比，使用 LAAO 装置进行 DRT 的患者缺血性中风的发生率仍相对降低了 28%。这表明这些中风可能源自 DRT 以外的其他病因。有活动性或已知癌症病史的患者似乎有较高的 DRT 风险。需要更多关于该主题的数据，以增强对 LAAO 并发症和 DRT 管理策略的认识和理解。