This study examined the feasibility and acceptability of two group-based interventions: group-cognitive behavioral therapy (G-CBT) and a family-strengthening intervention delivered via multiple family group (MFG-FS), to address HIV stigma among adolescents living with HIV (ALHIV) and their caregivers. A total of 147 adolescent -caregiver dyads from 9 health clinics situated within 7 political districts in Uganda were screened for eligibility. Of these, 89 dyads met the inclusion criteria and provided consent to participate in the study. Participants were randomized, at the clinic level, to one of three study conditions: Usual care, G-CBT or MFG-FS. The interventions were delivered over a 3-month period. While both adolescents and their caregivers attended the MFG-FS sessions, G-CBT sessions were only attended by adolescents. Data were collected at baseline, 3 and 6-months post intervention initiation. The retention rate was 94% over the study period. Across groups, intervention session attendance ranged between 85 and 92%, for all sessions. Fidelity of the intervention was between 85 and 100%, and both children and caregivers rated highly their satisfaction with the intervention sessions. ALHIV in Uganda, and most of sub–Saharan Africa, are still underrepresented in stigma reduction interventions. The Suubi4Stigma study was feasible and acceptable to adolescents and their caregivers –supporting testing the efficacy of the interventions in a larger trial.

本研究检验了两种基于群体的干预措施的可行性和可接受性：群体认知行为疗法（G-CBT）和通过多家庭小组提供的家庭强化干预措施（MFG-FS），以解决艾滋病毒感染青少年中的艾滋病毒耻辱问题（ALHIV）及其照顾者。对来自乌干达 7 个政治区 9 个卫生诊所的总共 147 名青少年和看护者进行了资格筛查。其中，89 人符合纳入标准并同意参与该研究。参与者在临床层面被随机分配至三种研究条件之一：常规护理、G-CBT 或 MFG-FS。干预措施的实施时间为 3 个月。虽然青少年及其照顾者都参加了 MFG-FS 课程，但只有青少年参加了 G-CBT 课程。在基线、干预开始后 3 个月和 6 个月收集数据。研究期间的保留率为 94%。在所有小组中，干预会议的出席率在 85% 到 92% 之间。干预的保真度在 85% 到 100% 之间，儿童和护理人员对干预课程的满意度都很高。乌干达和撒哈拉以南非洲大部分地区的 ALHIV 在减少耻辱干预措施中的代表性仍然不足。 Suubi4Stigma 研究是可行的，并且为青少年及其照顾者所接受——支持在更大规模的试验中测试干预措施的有效性。