Variability in plasma rifampicin concentrations and role of SLCO1B1, ABCB1, AADAC2 and CES2 genotypes in Ethiopian patients with tuberculosis,Infectious Diseases

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Variability in plasma rifampicin concentrations and role of SLCO1B1, ABCB1, AADAC2 and CES2 genotypes in Ethiopian patients with tuberculosis
Infectious Diseases ( IF 5.8 ) Pub Date : 2024-02-05 , DOI: 10.1080/23744235.2024.2309348
Tesemma Sileshi _{1,

2} , Eyasu Makonnen _{2,

3} , Nigus Fikrie Telele ₄ , Victoria Barclay ₄ , Alimuddin Zumla ₅ , Eleni Aklillu ₆

Affiliation

Rifampicin, a key drug against tuberculosis (TB), displays wide between-patient pharmacokinetics variability and concentration-dependent antimicrobial effect. We investigated variability in plasma ...

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