Glioblastoma (GBM) is a fatal adult central nervous system tumor. Due to its high heterogeneity, the survival rate and prognosis of patients are poor. Thousands of people die of this disease every year all over the world. At present, the treatment of GBM is mainly through surgical resection and the combination of later drugs, radiotherapy, and chemotherapy. An abnormal redox system is involved in the malignant progression and treatment tolerance of glioma, which is the main reason for poor survival and prognosis. The construction of a GBM redox-related prognostic model may be helpful in improving the redox immunotherapy and prognosis of GBM.

中文翻译：

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氧化还原基因在神经胶质瘤的预后和治疗反应中的意义。

胶质母细胞瘤（GBM）是一种致命的成人中枢神经系统肿瘤。由于其高度异质性，患者的生存率和预后较差。全世界每年有数千人死于这种疾病。目前GBM的治疗主要是通过手术切除以及后期药物、放疗、化疗相结合。氧化还原系统异常参与胶质瘤的恶性进展和治疗耐受，是其生存和预后不良的主要原因。GBM氧化还原相关预后模型的构建可能有助于改善GBM的氧化还原免疫治疗和预后。