Elevation of the systemic immune inflammation (SII) index and system inflammation response index (SIRI) is known to be associated with higher risk of stroke and all-cause death. However, no study has reported their correlation with early neurological deterioration (END) following recombinant tissue-type plasminogen activator (IV-rtPA) in acute ischemic stroke patients. The aim of this study was to explore the correlation of SII and SIRI with the risk of END after IV-rtPA.

中文翻译：

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2种新型炎症指标与急性缺血性中风患者静脉溶栓治疗后早期神经功能恶化风险的相关性。

众所周知，全身免疫炎症（SII）指数和系统炎症反应指数（SIRI）升高与中风和全因死亡风险升高相关。然而，尚无研究报道其与急性缺血性中风患者使用重组组织型纤溶酶原激活剂（IV-rtPA）后早期神经功能恶化（END）的相关性。本研究的目的是探讨 SII 和 SIRI 与 IV-rtPA 后 END 风险的相关性。