Liquid phase (or liquid cell) transmission electron microscopy (TEM) has become a powerful platform for in situ investigation of various chemical processes at the nanometer or atomic level. The electron beam for imaging can also induce perturbation to the chemical processes. Thus, it has been a concern that the observed phenomena in a liquid cell could deviate from the real-world processes. Strategies have been developed to overcome the electron-beam-induced issues. This article provides an overview of the electron-beam effects, and discusses various strategies in liquid cell TEM study of nucleation, growth, and self-assembly of nanoscale materials, where an electron beam is often used to initiate the reactions, and highly electron-beam-sensitive electrochemical reactions.

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中文翻译：

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克服液相 TEM 中电子束问题的策略：化学过程研究

液相（或液池）透射电子显微镜 (TEM) 已成为在纳米或原子水平上原位研究各种化学过程的强大平台。用于成像的电子束也会对化学过程产生扰动。因此，人们担心液体细胞中观察到的现象可能会偏离现实世界的过程。已经开发出克服电子束引起的问题的策略。本文概述了电子束效应，并讨论了纳米级材料的成核、生长和自组装的液体电池 TEM 研究中的各种策略，其中电子束通常用于引发反应，并且高度电子束光束敏感的电化学反应。

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