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Current treatment and immunomodulation strategies in Acute Myocarditis.
Journal of Cardiovascular Pharmacology ( IF 3 ) Pub Date : 2024-02-09 , DOI: 10.1097/fjc.0000000000001542
Emma Ferone 1 , Amitai Segev 2 , Erika Tempo 3 , Piero Gentile 4 , Ahmed Elsanhoury 5, 6, 7 , Chiara Baggio 8 , Jessica Artico 9, 10 , Prashan Bhatti 1, 11 , Paul Scott 11 , Emanuele Bobbio 12, 13 , Marco Merlo 8 , Pietro Ameri 3, 14 , Gianfranco Sinagra 8 , Carsten Tschöpe 5, 6, 7, 15 , Daniel Bromage 1, 11 , Antonio Cannata 1, 11
Affiliation  

Myocarditis is an inflammatory disease of the myocardium characterized by a great heterogeneity of presentation and evolution. Treatment of myocarditis is often supportive and the evidence for immunosuppression is scarce and debated. Conventional treatment is based on clinical presentation, ranging from conservative to advanced mechanical assist devices. In this setting, immunosuppression and immunomodulation therapies are mostly reserved for patients presenting with major clinical syndromes. In this review, we will summarise the current evidence and strategies for conventional and immunosuppressive treatments for patients presenting with acute myocarditis.

中文翻译:

急性心肌炎的当前治疗和免疫调节策略。

心肌炎是一种心肌炎症性疾病,其特征是表现和演变具有很大的异质性。心肌炎的治疗通常是支持性的,而免疫抑制的证据很少且存在争议。常规治疗基于临床表现,范围从保守到先进的机械辅助装置。在这种情况下,免疫抑制和免疫调节疗法主要用于出现主要临床综合征的患者。在这篇综述中,我们将总结针对急性心肌炎患者的常规和免疫抑制治疗的当前证据和策略。
更新日期:2024-02-09
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