Patient blood group (BG) is predictive for von-Willebrand-factor (VWF) and Factor VIII variation. The clinical impact of this ABO-effect on blood loss, cardiovascular complications and outcome has been described for several patient cohorts. The aim of this study was to investigate the impact of patient BG on blood loss and outcome after coronary artery bypass surgery (CABG). Patient records, intraoperative data and perioperative transfusion records of 5713 patients receiving an on-pump CABG procedure between 05/2004 and 12/2018 were analyzed. A logistic regression model for death due to perioperative myocardial ischaemia (PMI) was developed from initially 24 variables by using an univariate and multivariate selection process. BG AB patients required less blood transfusions as compared to the other blood groups, especially in case of emergency operations. However, BG AB patients also had a higher mortality which was due to secondary cardiovascular complications. The impact of blood type on the rate of cardiovascular mortality was confirmed in the logistic regression model. BG AB patients have a worse outcome after CABG surgery due to an increased incidence of fatal cardiovascular complications. As perioperative myocardial ischemia due to graft occlusion appears to be the most likely explanation, stricter anticoagulation for BG AB patients should be discussed.

患者血型 (BG) 可预测血管性血友病因子 (VWF) 和因子 VIII 变异。已经对多个患者队列描述了这种 ABO 效应对失血、心血管并发症和结果的临床影响。本研究的目的是调查患者 BG 对冠状动脉搭桥手术 (CABG) 后失血量和结果的影响。对 2004 年 5 月至 2018 年 12 月期间接受体外循环 CABG 手术的 5713 名患者的患者记录、术中数据和围手术期输血记录进行了分析。通过使用单变量和多变量选择过程，从最初的 24 个变量开发了围手术期心肌缺血 (PMI) 所致死亡的逻辑回归模型。与其他血型相比，BG AB 患者需要的输血较少，尤其是在紧急手术的情况下。然而，BG AB 患者由于继发性心血管并发症的死亡率也较高。血型对心血管死亡率的影响在逻辑回归模型中得到证实。由于致命性心血管并发症的发生率增加，BG AB 患者在 CABG 手术后预后较差。由于移植物闭塞导致围手术期心肌缺血似乎是最可能的解释，因此应讨论对 BG AB 患者进行更严格的抗凝治疗。