Abstract

Dihydropyrano[3,2-c]chromene derivatives have been synthesized by the one-pot three-component reaction of various aromatic aldehydes, malononitrile, and 4-hydroxycoumarin in aqueous ethanol (1:1) in the presence of Clay/APTS/Fe₃O₄ (cloisite-Na⁺/3-aminopropyltriethoxysilane/Fe₃O₄) magnetic nanoparticles as a novel catalyst. The structure of all products was elucidated by their FT-IR and ¹H NMR analysis. This one-pot three-component protocol provides an efficient improved pathway for the synthesis of chromenes in terms of short reaction times and simple experimental and workup procedures.

中文翻译：

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Clay/APTS/Fe3O4磁性纳米粒子——一种新型高效催化剂，用于合成4H,5H-吡喃并[3,2-c]色烯

摘要

在粘土/APTS/Fe存在下，各种芳香醛、丙二腈和4-羟基香豆素在乙醇水溶液（1:1）中通过一锅三组分反应合成了二氢吡喃并[3,2-c]色烯衍生物₃ O ₄ (cloisite-Na ⁺ /3-氨丙基三乙氧基硅烷/Fe ₃ O ₄ )磁性纳米颗粒作为新型催化剂。所有产物的结构均通过 FT-IR 和¹ H NMR 分析阐明。这种一锅三组分方案在短反应时间和简单的实验和后处理程序方面为色烯的合成提供了一种有效的改进途径。