Novel anti-neuroinflammatory pyranone-carbamate derivatives as selective butyrylcholinesterase inhibitors for treating Alzheimer’s disease,Journal of Enzyme inhibition and Medicinal Chemistry

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Novel anti-neuroinflammatory pyranone-carbamate derivatives as selective butyrylcholinesterase inhibitors for treating Alzheimer’s disease
Journal of Enzyme inhibition and Medicinal Chemistry ( IF 5.6 ) Pub Date : 2024-02-16 , DOI: 10.1080/14756366.2024.2313682
Chuanyu Yu ₁ , Xueyan Liu _{1,

2} , Bingxiang Ma ₃ , Jiexin Xu ₁ , Yiquan Chen ₁ , Chaoxian Dai ₁ , Huaping Peng ₃ , Daijun Zha _{1,

2}

Affiliation

Butyrylcholinesterase (BuChE) and neuroinflammation have recently emerged as promising therapeutic directions for Alzheimer’s disease (AD). Herein, we synthesised 19 novel pyranone-carbamate deriva...

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