The generation of clathrin-coated vesicles during endocytosis requires the co-ordinated recruitment of dozens of proteins to the plasma membrane. We discovered that the plant TPLATE (or TSET) complex (TPC) undergoes biomolecular condensation through interactions with plasma membrane phospholipids and, via weak multivalent interactions, recruits clathrin and other endocytic proteins to facilitate the efficient progression of endocytosis.

中文翻译：

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网格蛋白介导的内吞作用的有序和无序

胞吞过程中网格蛋白包被的囊泡的产生需要将数十种蛋白质协调地募集到质膜上。我们发现植物 TPLATE（或 TSET）复合物（TPC）通过与质膜磷脂的相互作用进行生物分子缩合，并通过弱多价相互作用，招募网格蛋白和其他内吞蛋白以促进内吞作用的有效进行。