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Increased incidence of adult gonococcal keratoconjunctivitis at two tertiary eye hospitals in Western Europe: clinical features, complications and antimicrobial susceptibility
British Journal of Ophthalmology ( IF 4.1 ) Pub Date : 2024-04-09 , DOI: 10.1136/bjo-2023-324750
Alice L Milligan , Anna C Randag , Sybren Lekkerkerk , Helen Fifer

Background Gonorrhoea is on the rise: between 2021 and 2022, a 50% and a 33% increase in diagnoses was seen, respectively, in England and the Netherlands. A concurrent rise in gonococcal keratoconjunctivitis (GKC) is a serious concern due to the potentially devastating visual complications. Methods This is a retrospective case series of adult GKC from two Western European tertiary ophthalmology centres between 2017 and July 2023. The clinical features, ocular complications and antimicrobial susceptibilities are reported within. Results An increased incidence was recorded at both centres, with 11 confirmed cases in the first 7 months of 2023, compared with ≤3 per year in 2017–2022. Conclusion The notable increase of GKC cases in our centres in 2023 may indicate a rise across Western Europe. Enhanced, sustained, national surveillance of GKC is essential to establish incidence and antimicrobial susceptibility, to inform treatment guidelines and guide appropriate public health response. All data relevant to the study are included in the article or uploaded as supplemental information.

中文翻译:

西欧两家三级眼科医院成人淋菌性角结膜炎发病率增加:临床特征、并发症和抗菌药物敏感性

背景 淋病呈上升趋势:2021 年至 2022 年间,英格兰和荷兰的诊断人数分别增加了 50% 和 33%。由于潜在的破坏性视觉并发症,淋菌性角结膜炎(GKC)的同时增加是一个严重的问题。方法 这是 2017 年至 2023 年 7 月期间来自两个西欧三级眼科中心的成人 GKC 的回顾性病例系列。其中报告了临床特征、眼部并发症和抗菌药物敏感性。结果 两个中心的发病率均有所增加,2023 年前 7 个月确诊病例为 11 例,而 2017-2022 年每年确诊病例数≤3 例。结论 2023 年,我们中心的 GKC 病例显着增加,可能表明整个西欧地区的 GKC 病例有所增加。加强、持续的国家 GKC 监测对于确定发病率和抗菌药物敏感性、为治疗指南提供信息并指导适当的公共卫生应对措施至关重要。与研究相关的所有数据都包含在文章中或作为补充信息上传。
更新日期:2024-04-10
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