This study introduces a new metal-free method using iodine (I₂) as a catalyst in aqueous conditions for synthesizing Streptindole and its derivatives. The approach is economically viable, easily handled, and exhibits remarkable tolerance to various functional groups. The protocol‘s versatility is showcased through the one-step total syntheses of alkaloid natural products Streptindole and Arsindoline B from indole.

中文翻译：

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水介质中碘催化合成链霉吲哚及其衍生物的新兴策略

本研究介绍了一种新的无金属方法，使用碘（I ₂）作为催化剂在水相条件下合成链霉吲哚及其衍生物。该方法经济可行，易于操作，并且对各种官能团表现出显着的耐受性。该方案的多功能性通过从吲哚一步全合成生物碱天然产物 Streptindole 和 Arsindoline B 来展示。