ObjectiveHematopoietic stem cell transplantation (HSCT) is considered an integral part of therapy in many hematological and non‐hematological malignancies. The procedure can be highly stressful for patients. The primary objective of this study was to compare stress assessments in HSCT patients, depending on their stress coping style (CS) and type of treatment (autologous vs. allogeneic HSCT).MethodsA short longitudinal study was conducted between May 2021 and June 2023 among patients with hematological cancers undergoing HSCT. The study involved four time points: the day of admission to hospital – T1, the day before HSCT – T2, 6 days after HSCT – T3, and the day of discharge – T4. Participants completed the Coping Inventory for Stressful Situations (CISS) on T1, and the Distress Thermometer (DT) on T1‐T4. Descriptive statistics and a repeated measures ANOVA were conducted.ResultsA total of 128 participants completed the study: 54.2% female, mean age 48.7 years. They were divided into: (1) five groups based on their CS: task‐oriented, emotion‐oriented, avoidance‐oriented, mix‐oriented, differential‐oriented; (2) two groups based on treatment type. The analyses showed significant differences in stress between the CS study groups (p = 0.001). The emotion‐oriented group had the highest stress levels during the hospitalization period. There was also a significant time effect (p < 0.001): stress levels increased during the hospitalization period, peaking 6 days after HSCT, and decreased at discharge.ConclusionsStress levels depend on coping styles and time points during the hospitalization period, which should be taken into account in planning psychological interventions for HSCT patients.

中文翻译：

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造血细胞移植患者的应对压力方式和感知压力水平

目的造血干细胞移植（HSCT）被认为是许多血液和非血液恶性肿瘤治疗的一个组成部分。该过程可能会给患者带来很大的压力。本研究的主要目的是比较 HSCT 患者的压力评估，具体取决于他们的压力应对方式 (CS) 和治疗类型（自体 HSCT 与同种异体 HSCT）。方法 2021 年 5 月至 2023 年 6 月在患者中进行了一项简短的纵向研究接受 HSCT 的血液癌症。该研究涉及四个时间点：入院当天——T1、HSCT前一天——T2、HSCT后6天——T3、出院当天——T4。参与者在 T1 上完成了压力情境应对清单 (CISS)，并在 T1-T4 上完成了应激温度计 (DT)。进行了描述性统计和重复测量方差分析。结果共有 128 名参与者完成了研究：54.2% 为女性，平均年龄 48.7 岁。他们根据CS分为：（1）五组：任务导向型、情绪导向型、回避导向型、混合导向型、差异导向型；(2)根据治疗类型分为两组。分析显示 CS 研究组之间的压力存在显着差异（p= 0.001）。情绪导向组在住院期间的压力水平最高。还存在显着的时间效应（p< 0.001)：住院期间压力水平升高，HSCT后6天达到峰值，出院时下降。结论压力水平取决于住院期间的应对方式和时间点，在对HSCT患者进行心理干预时应考虑到这一点。