We present the case of a gentleman who developed rapidly progressive vision loss, ophthalmo-paresis, and flaccid quadriparesis in the context of severe intracranial hypertension. We reviewed the available cases in the literature to increase awareness of this rare clinical entity.Case Report:A 36-year-old man developed rapidly progressive vision loss, ophthalmo-paresis, and flaccid quadriparesis. He had an extensive workup, only notable for severe intracranial hypertension, >55 cm of H2O. No inflammatory features were present, and the patient responded to CSF diversion. Few similar cases are available in the literature, but all show markedly elevated intracranial pressure associated with extensive neuroaxis dysfunction. Similarly, these patients improved with CSF diversion but did not appear to respond to immune-based therapies.

中文翻译：

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与多发性颅神经根神经病相关的颅内高压：病例报告和文献综述。

我们介绍了一位先生的病例，他在严重颅内高压的情况下出现了快速进行性视力丧失、眼部麻痹和弛缓性四肢瘫痪。我们回顾了文献中的现有病例，以提高对这种罕见临床实体的认识。病例报告：一名 36 岁男性出现快速进行性视力丧失、眼部麻痹和弛缓性四肢瘫痪。他接受了广泛的检查，仅因严重颅内高压（> 55 cm H2O）而值得注意。不存在炎症特征，患者对脑脊液改道有反应。文献中很少有类似的病例，但所有病例均显示颅内压显着升高，并伴有广泛的神经轴功能障碍。同样，这些患者通过脑脊液转移得到改善，但似乎对免疫疗法没有反应。