There are limited studies assessing modifiable preoperative risk factors for pediatric laparoscopic gastrostomy tubes (LGT) and percutaneous endoscopic gastrostomy (PEG) tubes. We sought to evaluate the effect of demographics and surgical/infectious history on the superficial infection rate following gastrostomy tube (GT) placement. After IRB approval, we conducted a single-institution retrospective cohort study from 2015-2021 of pediatric patients undergoing LGT or PEG tube. The primary outcome was cellulitis or abscess formation within 30-days and 90-days postoperatively. Statistical analyses were performed with t-tests, Chi-squared, and logistic regression(p≤0.05). There were 382 patients, with 181 (47%) LGT and 201 (53%) PEGs. LGT patients were younger (5.9 vs. 12.3 months, p<0.001) and more likely to be admitted to the neonatal or cardiac intensive care unit prior to their GT. There were similar rates of prior surgical intervention (58% vs. 66%, p=0.29) and previous infection (37% vs. 38%, p=0.87) in both LGT and PEG patients. Within 30-days postoperatively, LGT patients had a higher superficial infection rate (12% vs. 6%, p=0.04). On multivariate regression, Black race (Odds Ratio 0.10, p=0.03) was protective and prior colonization (OR 2.35, p=0.04) increased the odds of infection. In those patients colonized with , 21% developed a superficial site infection compared to 9% in those not colonized (p=0.01). These data suggest prior colonization is a significant risk factor for superficial infection following GT. Further work into preoperative decolonization strategies may provide an avenue to decrease the high infection rate in this common pediatric procedure. Level III

中文翻译：

---

可改变的术前危险因素可减轻小儿胃造口术后部位感染

目前评估儿科腹腔镜胃造口术 (LGT) 和经皮内窥镜胃造口术 (PEG) 管可改变的术前危险因素的研究有限。我们试图评估人口统计学和手术/感染史对胃造口管（GT）放置后浅表感染率的影响。在 IRB 批准后，我们​​对 2015 年至 2021 年接受 LGT 或 PEG 管的儿科患者进行了一项单机构回顾性队列研究。主要结局是术后 30 天内和 90 天内蜂窝组织炎或脓肿形成。通过t检验、卡方检验和逻辑回归进行统计分析（p≤0.05）。共有 382 名患者，其中 181 名（47%）LGT 和 201 名（53%）PEG。LGT 患者更年轻（5.9 个月 vs. 12.3 个月，p<0.001），并且更有可能在 GT 之前入住新生儿或心脏重症监护病房。LGT 和 PEG 患者的既往手术干预率（58% vs. 66%，p=0.29）和既往感染率（37% vs. 38%，p=0.87）相似。术后30天内，LGT患者的浅表感染率较高（12% vs. 6%，p=0.04）。在多变量回归中，黑人种族（比值比 0.10，p=0.03）具有保护性，而先前的定植（OR 2.35，p=0.04）增加了感染的可能性。在那些定植了 的患者中，21% 出现浅表部位感染，而未定植的患者中这一比例为 9% (p=0.01)。这些数据表明先前的定植是 GT 后浅表感染的重要危险因素。对术前去定植策略的进一步研究可能会为降低这种常见儿科手术中的高感染率提供途径。三级