Intercostal nerve cryoablation (INC) has been shown to reduce postoperative pain and length of stay following surgical correction of pectus excavatum (SCOPE). Some patients have developed chest wall dermatological symptoms after INC that can be mistaken for metal allergy or infection. The purpose of this study is to report the symptoms, severity, incidence, and treatment of post-cryoablation dermatitis. A retrospective single institution review was performed for patients who underwent SCOPE with and without INC between June 2016 and March 2023 to assess for incidence of postoperative dermatological findings. Characteristics associated with these findings were evaluated. During study period, 383 patients underwent SCOPE, 165 (43.1%) without INC and 218 (56.9%) with. Twenty-three (10.6%) patients who received INC developed exanthems characteristic of post-cryoablation dermatitis with two distinct phenotypes identified. No patients who underwent SCOPE without INC developed similar manifestations. Early dermatitis, characterized by a painless, erythematous, and blanching rash across the anterior thorax, was observed in 16 patients, presenting on median postoperative day 6.0 [IQR 6.0-8.5], with median time to resolution of 23.0 [IQR 12-71.0] days after symptom onset. Late dermatitis, characterized by hyperpigmentation spanning the anterior thorax, was observed in 7 patients, presenting on median postoperative day 129.0 [IQR 84.5-240.0], with median time to resolution of 114.0 [IQR 48.0-314.3] days. This is the first report of dermatological manifestations following SCOPE with INC, a phenomenon of unknown etiology and no known long-term sequela. In our experience, it is self-resolving and lacks systemic symptoms suggesting observation alone is sufficient for resolution. IV.

中文翻译：

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胸腔镜肋间神经冷冻消融手术矫正漏斗胸后的胸壁皮炎模式

肋间神经冷冻消融 (INC) 已被证明可以减少漏斗胸手术矫正 (SCOPE) 术后的疼痛和住院时间。一些患者在 INC 后出现胸壁皮肤病症状，可能被误认为是金属过敏或感染。本研究的目的是报告冷冻消融后皮炎的症状、严重程度、发病率和治疗方法。对 2016 年 6 月至 2023 年 3 月期间接受 SCOPE 联合或不联合 INC 的患者进行了回顾性单一机构审查，以评估术后皮肤病学发现的发生率。评估了与这些发现相关的特征。研究期间，383 名患者接受了 SCOPE，其中 165 名患者 (43.1%) 没有接受 INC，218 名患者 (56.9%) 接受了 SCOPE。接受 INC 治疗的 23 名患者 (10.6%) 出现了冷冻消融后皮炎的皮疹特征，并确定了两种不同的表型。在没有 INC 的情况下接受 SCOPE 的患者没有出现类似的表现。在 16 名患者中观察到早期皮炎，其特征是前胸出现无痛、红斑和变白皮疹，中位术后第 6 天出现 [IQR 6.0-8.5]，中位消退时间为 23.0 [IQR 12-71.0]症状出现后几天。在 7 名患者中观察到晚期皮炎，其特征是跨越前胸的色素沉着过度，中位术后天数为 129.0 天 [IQR 84.5-240.0]，中位消退时间为 114.0 天 [IQR 48.0-314.3] 天。这是 INC 术后 SCOPE 后皮肤病学表现的第一份报告，这种现象的病因不明，也没有已知的长期后遗症。根据我们的经验，它是自我解决的，并且缺乏全身症状，表明仅观察就足以解决问题。四．