Older persons with serious mental illness (SMI) have compromised physical function (endurance, strength, mobility). Multicomponent exercise is effective at improving function in older adults but has been minimally examined in older people with SMI. The purpose of this study was to evaluate changes in physical function for older adults with SMI enrolled in a clinical exercise program. This study was a retrospective analysis of Veterans Health Administration (VHA) electronic health record and national clinical exercise program (“Gerofit”) data. One hundred fifty older veterans with SMI and 1264 older veterans without SMI enrolled in eight Gerofit sites between 2010 and 2019. Veterans completed five objective measures of physical function assessing endurance (6-min walk test), strength (arm curl, chair stand), and mobility (10-m walk, 8-foot-up-and-go) at Gerofit enrollment and at three, six, and 12 months. Demographic and health information were obtained from VHA electronic health records. Propensity-score matching (1:3) was conducted followed by linear mixed modeling analyses to evaluate differences in trajectories of functional changes between groups. Results showed significant improvements in all function measures over time adjusting for SMI status and control variables; however, there were no significant differences in physical function changes between SMI and non-SMI groups. These findings suggest that multicomponent exercise can improve physical function in older veterans with SMI.

中文翻译：

---

患有严重精神疾病的老年退伍军人在临床锻炼计划中身体机能变化的轨迹

患有严重精神疾病（SMI）的老年人的身体功能（耐力、力量、活动能力）受到损害。多成分运动可有效改善老年人的功能，但在患有 SMI 的老年人中却很少受到研究。本研究的目的是评估参加临床锻炼计划的患有 SMI 的老年人身体机能的变化。这项研究是对退伍军人健康管理局 (VHA) 电子健康记录和国家临床锻炼计划 (“Gerofit”) 数据的回顾性分析。2010 年至 2019 年间，150 名患有 SMI 的老年退伍军人和 1264 名没有 SMI 的老年退伍军人在 8 个 Gerofit 站点注册。退伍军人完成了五项身体功能客观测量，评估耐力（6 分钟步行测试）、力量（手臂弯举、椅子站立）、 Gerofit 注册时以及 3、6 和 12 个月时的活动能力（10 米步行、8 英尺起立行走）。人口统计和健康信息是从 VHA 电子健康记录中获得的。进行倾向评分匹配（1:3），然后进行线性混合模型分析，以评估各组之间功能变化轨迹的差异。结果显示，随着时间的推移，根据 SMI 状态和控制变量进行调整，所有功能指标均显着改善；然而，SMI 组和非 SMI 组之间的身体功能变化没有显着差异。这些发现表明，多成分运动可以改善患有 SMI 的老年退伍军人的身体功能。