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Recent advances in nanomaterial-based drug delivery systems
Nano-Structures & Nano-Objects Pub Date : 2024-02-09 , DOI: 10.1016/j.nanoso.2024.101103
Vikram Jadhav , Arpita Roy , Kirtanjot Kaur , Ashutosh Kumar Rai , Sarvesh Rustagi

Nanotechnology is crucial to the chemical, physical and medicinal fields. Nanotechnology necessitates an understanding of the atomic and molecular structures of materials, so their application may be assessed. Due to their unique morphology, nanomaterials can be used as drug delivery systems for safe and effective therapies, where drugs can be given productively with minimal adverse effects. Nanomaterial drug carriers facilitate the transfer of proteins, nucleic acids and small biological molecules. They may help encapsulate drugs and enable more particular targeting with the controlled release of the drugs. Interest in developing and refining drug delivery agents has been sparked by the complexity of some illnesses and the inherent toxicity of some drugs; synthetic nanomaterials are generally preferable due to their unique physicochemical characteristics, such as easy preparation methods, superior biocompatibility and storage stability. There are several drug delivery systems built on inorganic-based nanomaterials. Even though there are still many challenges to be solved, tremendous progress has been achieved recently. The review presented here focuses on the state and development of inorganic-based nanomaterials, such as carbon-based, silica-based and iron oxide, that may transport chemical and biological drug molecules. This article outlines the development of nanomaterials for drug delivery systems and information about the most recent products in drug delivery research and technology.

中文翻译:

基于纳米材料的药物输送系统的最新进展

纳米技术对于化学、物理和医学领域至关重要。纳米技术需要了解材料的原子和分子结构,因此可以评估它们的应用。由于其独特的形态,纳米材料可用作安全有效治疗的药物输送系统,可以有效地给药,且副作用最小。纳米材料药物载体有利于蛋白质、核酸和生物小分子的转移。它们可以帮助封装药物并通过药物的受控释放实现更具体的靶向。某些疾病的复杂性和某些药物的固有毒性激发了人们对开发和精炼药物递送剂的兴趣;合成纳米材料由于其独特的物理化学特性,例如简单的制备方法、优异的生物相容性和储存稳定性而通常受到青睐。有几种基于无机纳米材料的药物输送系统。尽管仍有许多挑战有待解决,但最近已经取得了巨大进展。本文的综述重点关注无机纳米材料的现状和发展,例如碳基、二氧化硅基和氧化铁,这些材料可以运输化学和生物药物分子。本文概述了药物输送系统纳米材料的发展以及药物输送研究和技术最新产品的信息。
更新日期:2024-02-09
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