To perform posturographic measurements with eyes open or closed using floor coverings with different textured surfaces to study postural control in patients with multiple sclerosis (MS). Static posturographic recordings were performed with eyes open and eyes closed on a forceplate with no covering (control condition) or covered by a textured mat with small pimples (height 2 mm) or large pimples (height 7 mm). Several posturographic variables were measured, focusing on displacements of the center of pressure (CoP) including the average velocity (V), the total length (L) of all displacements, and the surface (S) of the confidence ellipse. The recordings made with the textured mats were compared to the control condition with eyes open or closed. Then, the differences between the recordings made with large vs. small pimples on the one hand, and with eyes closed vs. open were calculated to assess the impact of pimple height or eye closure on posturographic measurements. Clinical assessment was based on the Expanded Disability Status Scale (EDSS) and its functional system (FS) subscores, the Modified Fatigue Impact Scale (MFIS), the Unipodal Stance test (UST), and the Timed Up-and-Go test (TUG). Forty-six MS patients (mean EDSS score: 3.6) completed the study. Several posturographic variables, including V and L, deteriorated when measured on a textured mat, especially with large pimples and in eyes open condition. In contrast, no difference was found with small pimples and eyes closed, as compared to the control condition (no covering). The deleterious impact of pimple height on posturography correlated positively with the alteration of balance and gait clinically assessed by the UST and the TUG, and also with the MFIS physical and cerebral EDSS-FS subscores, and negatively with the cerebellar and brainstem subscores. On the other hand, the impact of eye closure on posturography was negatively correlated with the visual EDSS-FS subscore. Static posturographic measurements made with different textured surfaces and visual conditions can be considered as a sensitive tool to measure "proprioceptive reserves". Actually, when cerebellar, brainstem, or visual functions are impaired, the resources of the sensory (proprioceptive) system, if preserved, can be recruited at a higher level and compensate for dysfunctions of other postural controls to maintain a satisfactory balance. In addition, this procedure of static posturographic examination can provide objective measurements correlated with clinical testing of balance and gait and could usefully complement EDSS scoring to assess disability affecting postural control and the risk of falling in MS patients.

中文翻译：

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纹理表面对多发性硬化症患者直立平衡的影响

使用具有不同纹理表面的地板覆盖物进行睁眼或闭眼的姿势测量，以研究多发性硬化症 (MS) 患者的姿势控制。静态姿势记录是在没有覆盖物（对照条件）或用带有小丘疹（高度 2 mm）或大丘疹（高度 7 mm）的纹理垫覆盖的测力板上睁开眼睛并闭上眼睛进行的。测量了几个体态变量，重点关注压力中心 (CoP) 的位移，包括平均速度 (V)、所有位移的总长度 (L) 以及置信椭圆的表面 (S)。将使用纹理垫进行的录音与睁眼或闭眼的对照条件进行比较。然后，计算一方面用大丘疹与小丘疹、闭眼与睁眼进行的记录之间的差异，以评估丘疹高度或眼睛闭合对姿势测量的影响。临床评估基于扩展残疾状态量表 (EDSS) 及其功能系统 (FS) 子评分、改良疲劳影响量表 (MFIS)、单足站立测试 (UST) 和定时起立测试 (TUG) ）。46 名 MS 患者（平均 EDSS 评分：3.6）完成了这项研究。在有纹理的垫子上测量时，包括 V 和 L 在内的几个姿势变量会恶化，特别是在有大丘疹和睁眼的情况下。相反，与对照条件（无遮盖物）相比，在小丘疹和闭眼的情况下没有发现差异。丘疹高度对姿势描记术的有害影响与 UST 和 TUG 临床评估的平衡和步态改变呈正相关，也与 MFIS 身体和大脑 EDSS-FS 子评分呈正相关，与小脑和脑干子评分呈负相关。另一方面，闭眼对姿势描记法的影响与视觉 EDSS-FS 子评分呈负相关。使用不同纹理表面和视觉条件进行的静态姿势测量可以被视为测量“本体感受储备”的敏感工具。事实上，当小脑、脑干或视觉功能受损时，如果保留感觉（本体感觉）系统的资源，则可以在更高水平上募集并补偿其他姿势控制的功能障碍，以保持令人满意的平衡。此外，这种静态姿势检查程序可以提供与平衡和步态临床测试相关的客观测量，并且可以有效地补充 EDSS 评分，以评估影响姿势控制的残疾和 MS 患者跌倒的风险。