The effects of genetic polymorphism on toxicity and pharmacokinetics of methotrexate in Egyptian adult patients with leukaemia or lymphoma,Xenobiotica

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The effects of genetic polymorphism on toxicity and pharmacokinetics of methotrexate in Egyptian adult patients with leukaemia or lymphoma
Xenobiotica ( IF 1.8 ) Pub Date : 2024-03-05 , DOI: 10.1080/00498254.2024.2320778
Khloud Shendy ₁ , Khaled Abdelkawy ₁ , Ahmed Amin Ali ₁ , Fathalla Belal ₂ , Mostafa Abdelhakiem ₃ , Galal Magdy ₄ , Nahla Anber ₅ , Fawzy Elbarbry ₆

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Polymorphisms in genes coding folate-metabolising enzymes might alter the pharmacokinetics and sensitivity for methotrexate “MTX”.The aim of the study aimed to investigate the influence of MTHFR C6...

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