Proton therapy is sensitive to anatomical changes, often occurring in head-and-neck (HN) cancer patients. Although multiple studies have proposed online adaptive proton therapy (APT), there is still a concern in the radiotherapy community about the necessity of online APT. We have performed a retrospective study to investigate the potential dosimetric benefits of online APT for HN patients relative to the current offline APT.

中文翻译：

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在线自适应质子治疗头颈癌潜在剂量学益处调查的回顾性研究

质子治疗对解剖学变化敏感，通常发生在头颈 (HN) 癌症患者中。尽管多项研究提出了在线自适应质子治疗（APT），但放射治疗界仍然对在线APT的必要性存在担忧。我们进行了一项回顾性研究，以调查相对于当前离线 APT 而言，在线 APT 对 HN 患者的潜在剂量学益处。