Chronic visceral hypersensitivity is closely associated with irritable bowel syndrome (IBS), a very common disorder which significantly impairs quality of life, characterized by abdominal pain, and distension. Imaging studies have found that IBS patients show higher metabolic activities and functional differences from normal controls in the anterior cingulate cortex (ACC), in response to visceral pain stimulation. Non-clinical data and clinical data suggest that medicinal products containing essential oils such as peppermint or caraway oil exert beneficial effects on IBS symptoms.

中文翻译：

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薄荷卡林治疗可减轻内脏过敏模型中的伤害感受

慢性内脏过敏与肠易激综合症（IBS）密切相关，这是一种非常常见的疾病，会严重损害生活质量，其特征是腹痛和腹胀。影像学研究发现，IBS 患者在应对内脏疼痛刺激时，前扣带皮层 (ACC) 的代谢活动与正常对照相比表现出更高的代谢活动和功能差异。非临床数据和临床数据表明，含有薄荷油或香菜油等精油的药品对肠易激综合征症状有有益作用。