The relationship between metabolism and cardiovascular diseases is complex and bidirectional. Cardiac cells must adapt metabolic pathways to meet biosynthetic demands and energy requirements to maintain contractile function. During cancer, this homeostasis is challenged by the increased metabolic demands of proliferating cancer cells.

中文翻译：

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癌症患者心功能障碍的代谢基础。

代谢与心血管疾病之间的关系是复杂的、双向的。心肌细胞必须适应代谢途径以满足生物合成需求和维持收缩功能的能量需求。在癌症期间，这种稳态受到增殖癌细胞代谢需求增加的挑战。