: Cancer is characterized by the uncontrolled proliferation and spread of abnormal cells in the body, resulting in the development of tumors or clusters of irregular cells. The factors contributing to cancer are intricate, involving a combination of genetic, environmental, and lifestyle elements. Risk factors for cancer include the use of nicotine, excessive alcohol consumption, exposure to radiation or specific chemicals, and a family history of the disease. Common treatment methods for cancer encompass surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy. These treatments aim to eliminate cancer cells while minimizing harm to healthy cells. Recent research has extensively explored the potential of bioactive compounds as agents for combating cancer. However, effectively delivering such compounds to specific target sites is a complex undertaking. Consequently, there has been widespread exploration of polymer applications in the development of nanomedicine for delivering bioactive substances. Additionally, the technique of grafting native excipients onto polymers has been investigated to enhance their versatility in the delivery of these compounds to specific tumor cells. This review offers a brief yet informative summary of how grafted chitosan is employed as a delivery system for bioactive phytopharmaceuticals possessing anticancer properties. In essence, it delves into the use of grafted chitosan in facilitating the transport and targeted release of these natural compounds that have demonstrated potential in combating cancer. This innovative approach has the potential to enhance the effectiveness of anticancer treatments and minimize their adverse effects on healthy cells.

中文翻译：

---

移植壳聚糖强化生物活性剂的先进靶向药物递送在癌症治疗中的应用：综述

：癌症的特点是体内异常细胞不受控制的增殖和扩散，导致肿瘤或不规则细胞簇的发展。导致癌症的因素很复杂，涉及遗传、环境和生活方式因素的结合。癌症的危险因素包括使用尼古丁、过量饮酒、接触辐射或特定化学物质以及该疾病的家族史。癌症的常见治疗方法包括手术、放射治疗、化疗、免疫治疗和靶向治疗。这些治疗旨在消除癌细胞，同时最大限度地减少对健康细胞的伤害。最近的研究广泛探索了生物活性化合物作为抗癌药物的潜力。然而，有效地将此类化合物递送至特定目标位点是一项复杂的任务。因此，在开发用于输送生物活性物质的纳米医学中聚合物的应用得到了广泛的探索。此外，还研究了将天然赋形剂接枝到聚合物上的技术，以增强其将这些化合物递送至特定肿瘤细胞的多功能性。这篇综述对如何将接枝壳聚糖用作具有抗癌特性的生物活性植物药物的输送系统进行了简短而内容丰富的总结。从本质上讲，它深入研究了使用接枝壳聚糖来促进这些天然化合物的运输和靶向释放，这些天然化合物已被证明具有抗癌潜力。这种创新方法有可能提高抗癌治疗的有效性并最大限度地减少其对健康细胞的不利影响。