The Asthma Impairment and Risk Questionnaire (AIRQ) is a 10-item, yes/no, equally weighted control tool. Lower scores indicate better control. Moreover, 7 impairment items reflect previous 2-week symptoms, and 3 risk items assess previous 12-month exacerbations. The Follow-up AIRQ for use between annual assessments has a 3-month recall period for exacerbation items. To evaluate the responsiveness of the AIRQ over time and identify a minimal important difference (MID). The AIRQ longitudinal study data were analyzed from patients with asthma aged 12 years and older. Anchor-based methods assessed differences in AIRQ scores relative to Patient Global Impression of Change, the accepted MIDs for St. George's Respiratory Questionnaire and Asthma Control Test, and exacerbation occurrence over 12 months. Baseline and 12-month data reflected 12-month recall AIRQ scores; Follow-up AIRQ scores were used for 3-, 6-, and 9-month analyses. A total of 1070 patients were included. The Patient Global Impression of Change rating of “much improved” was associated with AIRQ mean score changes from baseline to months 3, 6, 9, and 12 of −2.0, −1.9, −1.9, and −1.8, respectively. The mean AIRQ score change among patients who met the St. George's Respiratory Questionnaire MID (≥4-point decrease) was −1.8 at 6 and 12 months. The AIRQ mean scores decreased from baseline by −2.2 to −2.5 points at months 3, 6, 9, and 12 for patients who met the Asthma Control Test MID (≥ 3-point increase). A 2-point higher baseline AIRQ score was associated with a 1.7 odds ratio of 12-month exacerbation occurrence (95% CI, 1.53-1.89). A change score of 2 is recommended as the AIRQ MID.

中文翻译：

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评估哮喘损伤和风险问卷的有意义的变化

哮喘损伤和风险问卷 (AIRQ) 是一个包含 10 项、是/否、同等权重的控制工具。分数越低表明控制能力越好。此外，7 个损伤项目反映了之前 2 周的症状，3 个风险项目评估了之前 12 个月的恶化情况。在年度评估之间使用的后续 AIRQ 对于恶化项目有 3 个月的召回期。评估 AIRQ 随着时间的推移的响应能力并确定最小重要差异 (MID)。 AIRQ 纵向研究数据对 12 岁及以上哮喘患者进行分析。基于锚定的方法评估了 AIRQ 评分相对于患者总体变化印象、圣乔治呼吸问卷和哮喘控制测试公认的 MID 以及 12 个月内病情加重发生情况的差异。基线和 12 个月数据反映了 12 个月回忆 AIRQ 分数；后续 AIRQ 评分用于 3、6 和 9 个月的分析。总共包括 1070 名患者。患者总体印象变化评级“大大改善”与 AIRQ 平均评分从基线到第 3、6、9 和 12 个月的变化相关，分别为 -2.0、-1.9、-1.9 和 -1.8。符合圣乔治呼吸问卷 MID（下降≥4分）的患者在 6 个月和 12 个月时的平均 AIRQ 评分变化为 -1.8。对于符合哮喘控制测试 MID 的患者，AIRQ 平均评分在第 3、6、9 和 12 个月从基线下降了 -2.2 至 -2.5 分（增加≥ 3 分）。基线 AIRQ 评分高 2 分与 1.7 的 12 个月恶化发生率相关（95% CI，1.53-1.89）。建议将 AIRQ MID 的更改分数设置为 2。