Objective/backgroundA previous study showed that geranium essential oil predominantly affects the parasympathetic nervous system. This article examined the effects on the autonomic nervous system of linalool, one of the main components of geranium essential oil.MethodsMice were placed on a narrow elevated open platform and pulse wave measurements were taken while they were awake, with behaviors restricted. Heart rate and heart rate variability were analyzed from the pulse waves obtained and the effects on the parasympathetic and sympathetic nerves were examined.ResultsThe results showed that linalool (5 μL/L air, inhaled) resulted in parasympathetic dominance before and after administration. Conversely, a tendency toward sympathetic dominance was observed with fluoxetine (1 mg/kg, intraperitoneal) as the positive control in the elevated open-platform test.ConclusionThese results suggest that linalool and essential oils containing linalool regulate the autonomic nervous system by promoting dominance of the parasympathetic nervous system.

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吸入芳樟醇对清醒小鼠自主神经系统的影响

目的/背景之前的一项研究表明，天竺葵精油主要影响副交感神经系统。本文研究了天竺葵精油的主要成分之一芳樟醇对自主神经系统的影响。方法将小鼠置于狭窄的高架开放平台上，在清醒时测量脉搏波，并限制其行为。从获得的脉搏波中分析心率和心率变异性，并检查对副交感神经和交感神经的影响。结果结果显示，芳樟醇（5μL/L空气，吸入）在给药前后导致副交感神经优势。相反，在高架开放平台试验中，以氟西汀（1 mg/kg，腹腔注射）作为阳性对照，观察到交感神经占优势的趋势。结论这些结果表明，芳樟醇和含有芳樟醇的精油通过促进交感神经的优势来调节自主神经系统。副交感神经系统。